Browsing by Author "Sagredo, Eduardo A."

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    • TRPM4 channel is involved in regulating epithelial to mesenchymal transition, migration, and invasion of ... 
      Sagredo, Alfredo I.; Sagredo, Eduardo A.; Pola, Victor; Echeverría, César; Andaur, Rodrigo; Michea Acevedo, Luis; Stutzin Schottlander, Andrés; Simon, Felipe; Marcelain Cubillos, Katherine; Armisén, Ricardo (Wiley, 2019)
      Transient Receptor Potential Melastatin 4 (TRPM4) is a Ca2+‐activated and voltage‐ dependent monovalent cation channel, which depolarizes the plasma cell membrane, thereby modulating Ca2+ influx across Ca2+‐permeable ...
    • TRPM4 regulates Akt/GSK3-b activity and enhances b-catenin signaling and cell proliferation in prostate ... 
      Sagredo, A.; Sagredo, Eduardo A.; Cappelli, Claudio; Baez, Pablo; Andaur, Rodrigo E.; Blanco, Constanza; Tapia, Julio C.; Echeverría, César; Cerda, Oscar; Stutzin Schottlander, Andrés; Simon, Felipe; Marcelain Cubillos, Katherine; Armisen Yáñez, Ricardo (John Wiley, 2018)
      Increased expression of the TRPM4 channel has been reported to be associated with the progression of prostate cancer. However, the molecular mechanism underlying its effect remains unknown. This work found that decreasing ...